this condition is called pompholyx
the treatment would be application of steroid cream like mometasone
furoate 0.1% once a day for 10 days over the palms and
oral antihistaminic tablet like tab. loratidine
5 mg once a day will help you out with the itching.
in case there is any pus filled lesion, then it is infected, a topical antibiotic
cream i.e fucidin will be effective.
in case you sweat a lot over your palms that will have to be taken care of as well.
please feel free to ask me in case you have any queries.