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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Itching And Redness In The Eye. Blood Test Showing Eosinophilia. Could This Be Related To Worm Infestation?

hi
I intense itching and redness of the right left eye and blood level showed esinophilia. I have no history of allergy or asthma. I was prescibed anti allergic eye drops which did not work. then I passed out worm. I realised that must have been the cause so I took a worm expellant.
Is it possible that the worm could have invaded my cNS or was this just a systemic reaction of eosinophila in the blood
at work level of infestation will it cause eye symptoms like i had and what type of worm do u think was it.
This happened in Africa.

Thank you
Tue, 9 Apr 2013
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Internal Medicine Specialist 's  Response

HI

LOA LOA Filariasis such as loiasis most often consists of asymptomatic microfilaremia. Some patients develop lymphatic dysfunction causing lymphedema. Episodic angioedema (Calabar swellings) in the arms and legs, caused by immune reactions are common. When chronic, they can form cyst-like enlargements of the connective tissue around the sheaths of muscle tendons, becoming very painful when moved. The swellings may last for 1–3 days, and may be accompanied by localized urticaria (skin eruptions) and pruritus (itching). Subconjunctival migration of an adult worm to the eyes can also occur frequently, and this is the reason Loa loa is also called the "African eye worm." The passage over the eyeball can be sensed, but it usually takes less than 15 min. Gender incidence of eyeworms have approximately the same frequency, but it tends to increase with age. Eosinophilia is often prominent in filarial infections. Dead worms may cause chronic abscesses, which may lead to the formation of granulomatous reactions and fibrosis.
TAKE CARE
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Allergist and Immunologist Dr. Sujoy Khan's  Response
Hello,

Eosinophilia and raised IgE are responses of the immune system to parasites, namely worms.

High levels of eosinophil on degranulation cause several symptoms, and also affect the eye such as eye redness, itching.
Raised levels can also affect the lung, and manifest as asthma.

Specifically, loa loa disease affects the eye and causes eosinophil levels to rise.


Best Wishes for a speedy recovery.
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Itching And Redness In The Eye. Blood Test Showing Eosinophilia. Could This Be Related To Worm Infestation?

HI LOA LOA Filariasis such as loiasis most often consists of asymptomatic microfilaremia. Some patients develop lymphatic dysfunction causing lymphedema. Episodic angioedema (Calabar swellings) in the arms and legs, caused by immune reactions are common. When chronic, they can form cyst-like enlargements of the connective tissue around the sheaths of muscle tendons, becoming very painful when moved. The swellings may last for 1–3 days, and may be accompanied by localized urticaria (skin eruptions) and pruritus (itching). Subconjunctival migration of an adult worm to the eyes can also occur frequently, and this is the reason Loa loa is also called the African eye worm. The passage over the eyeball can be sensed, but it usually takes less than 15 min. Gender incidence of eyeworms have approximately the same frequency, but it tends to increase with age. Eosinophilia is often prominent in filarial infections. Dead worms may cause chronic abscesses, which may lead to the formation of granulomatous reactions and fibrosis. TAKE CARE