Hi, I ve gone through your query and I understand quite well your concern Since pregnancy is a very delicate state, we can say that no drug is 100 percent safe for all women. We have to be careful with any drug, even with over-the-counter medication or OTC drugs. Ampiclox is ampicillin antibiotic while Emzolyn is an expectorant that helps you to loose cough secretions. No adequate human data but suggested possible association with cardiovascular defects in 1st trimester exposure. You should also know that: no adequate and well-controlled studies on pregnant women are done and no fetal adverse effects has been reported with ampicillin use in pregnancy. I recommend you the following safe cough medicine for pregnant women to take: -Guaifenesin – it stimulates expectoration and clears the respiratory system -Dextromethorphan – suppresses cough -Vicks VapoRub - an ointmentapplied on the throat and chest to suppress cough and alleviate muscles. Meanwhile, I suggest you some home remedies which are natural and totally safe to relieve cough instead of medications: 1. Drink plenty of water, fruit and fresh juices 2. avoid coffee and soda drinks 3. Gargling with warm water and salt in it, will relieve a sore throat and cough. 4. an effective remedy to relieve cough :a tea prepared with ginger, lemon and honey 5. eat garlic, take vitamin C and omega 3 fatty acids which boost immune system 6. Eat more organic foods and take vitamin supplements. Wish you good health Dr. Ermira Biu