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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Get Pregnant With RH Negative?

Should I get pregnant agin? The fetus has not been vialble since week 7 and I started spotting two weeks ago. I would now be 12 weeks pregnant. The doctor that I saw that time called me 10 days ago to tell me that I was RH-negative and to wait till my next period before I get labs done and get my RHOgam shot. I didn't even know prior to this that I was RH negetive or what it ment. Reading up on the RH factor everything I read said 72 hours after. I went for a second opinion and he recomended to get it now, almost two weeks after I started spotting. I still will follow up with my lab work, to find out if I have the antibodies capable of attacking an RH-positive fetus, and if I do How dangerous is getting pregnant again?
Tue, 3 Nov 2015
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OBGYN,  's  Response
Hi,

So you have had a missed abortion and are spotting from 9 weeks.
You do not need to take Anti D (RHOGAM) and do not need to worry about RH factor as yet. The reasons are..
Anti D (Rhogam ) is not given in abortion less than 12 weeks .
Anti D is most effective 72 hours after sensitizing event(Abortion,fetal death,delivery ,trauma to abdomen), but can be given upto 10 days.
Also, before you worry so much, I would like to know your partners blood group, if he is also Rh negative you need not worry at all.
Even if he is Rh postive but heterozygous to Rh there is a 50% chance that your baby will Rh negative and you will not need Anti D.

It is not at all dangerous for you to get pregnant. You can consider getting pregnant as soon as you are mentally and physically ready.

You could inform the obstetrician in next pregnancy and she could check fetal Rh by a technology called Cell-free fetal DNA. If this confirms that your baby is Rh negative, then you don't need extra monitoring. If this shows the baby is Rh positive, she could monitor you and inform the neonatalogist when baby is born. Also take Anti D then after delivery if baby is Rh positive.

Hope this helps.
Regards.
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Is It Safe To Get Pregnant With RH Negative?

Hi, So you have had a missed abortion and are spotting from 9 weeks. You do not need to take Anti D (RHOGAM) and do not need to worry about RH factor as yet. The reasons are.. Anti D (Rhogam ) is not given in abortion less than 12 weeks . Anti D is most effective 72 hours after sensitizing event(Abortion,fetal death,delivery ,trauma to abdomen), but can be given upto 10 days. Also, before you worry so much, I would like to know your partners blood group, if he is also Rh negative you need not worry at all. Even if he is Rh postive but heterozygous to Rh there is a 50% chance that your baby will Rh negative and you will not need Anti D. It is not at all dangerous for you to get pregnant. You can consider getting pregnant as soon as you are mentally and physically ready. You could inform the obstetrician in next pregnancy and she could check fetal Rh by a technology called Cell-free fetal DNA. If this confirms that your baby is Rh negative, then you don t need extra monitoring. If this shows the baby is Rh positive, she could monitor you and inform the neonatalogist when baby is born. Also take Anti D then after delivery if baby is Rh positive. Hope this helps. Regards.