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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Discontinue Azilect Prescribed For Parkinson S Disease?

Hi I am currently well was currently taking azilect 1mg for parkinsons and was recently taken off of it ( yesterday) I haven t been taking my anit-depressant medication because the pharmacy didn t fill it even tho it s on automatic refill and I ve been taking it for awhile and nothing has happened and nobody has noticed til recenently. like 2 or so months ago. They say the reason is because they counteract with each other but I haven t been given a formal reason
Tue, 27 Jun 2017
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Neurologist 's  Response
Hello:

Azilect is used to control Parkinson's Disease symptoms (slow movement and tremor, basically). If you discontinue it, you could be suffering from those symptoms.

Some antidepressants can interact with azilect, increasing serotonin levels up to a critical level, causing potentially life threatening reactions as serotonin syndrome (agitation, restlessness, diarrhea, tachycardia, hallucinations, hyperthermia, nausea and vomiting, hyperreflexia, hypertension), or neuroleptic malignant syndrome (rigidity, diaphoresis, dyspnea, dysphagia, gait abnormalities, hyperthermia, incontinence, pallor, drooling, delirium, stupor or even coma).

I suggest consulting with your neurologist and talk about it, maybe the doctor can adjust your treatment, choosing another kind of drug for Parkinson's Disease, or maybe (If there is no other choice) choose the right antidepressant for you.

I hope this helps, if you have any doubt before your appointment, please let me know.
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Is It Safe To Discontinue Azilect Prescribed For Parkinson S Disease?

Hello: Azilect is used to control Parkinson s Disease symptoms (slow movement and tremor, basically). If you discontinue it, you could be suffering from those symptoms. Some antidepressants can interact with azilect, increasing serotonin levels up to a critical level, causing potentially life threatening reactions as serotonin syndrome (agitation, restlessness, diarrhea, tachycardia, hallucinations, hyperthermia, nausea and vomiting, hyperreflexia, hypertension), or neuroleptic malignant syndrome (rigidity, diaphoresis, dyspnea, dysphagia, gait abnormalities, hyperthermia, incontinence, pallor, drooling, delirium, stupor or even coma). I suggest consulting with your neurologist and talk about it, maybe the doctor can adjust your treatment, choosing another kind of drug for Parkinson s Disease, or maybe (If there is no other choice) choose the right antidepressant for you. I hope this helps, if you have any doubt before your appointment, please let me know.