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Is it possible for a person with Hodgkin's or Non-Hodgkin's lymphoma to have normal CBC ?

Is it possible for a person with hodgkins or non hodgkins lymphoma to have a normal CBC
Asked On : Sat, 11 Feb 2012
Answers:  2 Views:  94
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Oncologist, Radiation 's  Response
yes, majority time its normal count of blood,.
lymphadenopathy is a major factor to involve many site,.
there may be extralymphatic to be involved.
diagnosis is by excision biopsy of involved lymphnode followed by IMMUNO HISTOCHEMISTRY TOfinalize between NHL Vs HD.
Answered: Fri, 13 Apr 2012
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Pathologist and Microbiologist Dr. M Agarwal's  Response
Hello. Welcome to HCM.
Hodgkin's and non-Hodgkin's lymphomas are a group of lymphoid neoplasms involving primarily the lymph nodes and in later stages also the bone marrow and sometimes other lympho-reticular organs like liver and spleen. Until a lymphoma does not involve the bone marrow (which is the site of production of blood cells), the person will have normal CBC. It is only when the lymphoid cells start replacing normal hematopoetic cells, that the normal RBC, WBC and platelets start getting depleted and ultimately, the lymphoma cells may spill over into the peripheral blood.
Hope The answer is clear. Take care.
Answered: Sat, 11 Feb 2012
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