Hello, and I hope I can help you today. In the first trimester of pregnancy, your ovaries produce the hormone progesterone which normally is made by the placenta once it reaches adequate size. So it is not unusual in the first trimester pregnancy to feel pain in your ovaries. In addition, as your uterus stretches, you also may experience some cramping and pulling sensations, which can be on the sides. The only thing that is concerning is if you have not had an ultrasound this pregnancy to confirm that it is normal and located in your uterus. If you already have had an ultrasound for this pregnancy it is unlikely that there could be anything harmful going on, especially if you are not bleeding. So if the pain is severe enough that you cannot function, especially if you have not yet had an ultrasound, if you cannot reach her doctor within a reasonable amount of time, you may want to pursue care in an emergency setting. If you have had a normal ultrasound earlier in this pregnancy, you really do not need to worry, as your ovaries are normally examined as part of your pregnancy ultrasound and a large cyst would ve already been detected. Tylenol, or acetaminophen is safe to use for pain at the normal adult dosage during all trimesters of pregnancy and you can try to see if that helps with the pain. I hope that I was able to adequately answer your question today, and that my advice was helpful. Best wishes for the rest of the pregnancy, Dr. Brown