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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Dry Skin Along With Premature Greying Of Hair Due To Votrient?

I have stage 4 RCC only have 90%of right kidney, left kidney removed in 2003. April 2015 found by scan exam 1 inch mass in remaining right kidney and 2 masses in pancreas one in tail and one in body . Taking votrent 800 MG per day however did not understand that was to be taken all in one dose and have taken 200 MG 4 times per day starting early morning until late at night between meal. First and last scan after 3 months indicated slight shrinkage of masses. Have some side effects such as white hair , gastric issues, extremely dry skin,etc. How severe of a effect has been created by taking dosages as I have ?
Mon, 20 Jun 2016
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General & Family Physician 's  Response
Hi,
Thanks for posting in HCM.
I understand your concern.
Votrient contains pazopanib, which is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Pazopanib is used mainly to treat kidney cancer.
Experiencing dry skin & hair, nausea, gastrointestinal disturbances and hair loss or hair colour change is one of the common side effects experienced by the use of the drug.
However, most of these changes are temporary and normal hair growth should return after treatment has ended. Symptomatic treatment should suffice to overcome such side effects. If these effects persist or worsen, you need to seek medical attention promptly.
Hope the information provided would be helpful.
All the best.
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Is Dry Skin Along With Premature Greying Of Hair Due To Votrient?

Hi, Thanks for posting in HCM. I understand your concern. Votrient contains pazopanib, which is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Pazopanib is used mainly to treat kidney cancer. Experiencing dry skin & hair, nausea, gastrointestinal disturbances and hair loss or hair colour change is one of the common side effects experienced by the use of the drug. However, most of these changes are temporary and normal hair growth should return after treatment has ended. Symptomatic treatment should suffice to overcome such side effects. If these effects persist or worsen, you need to seek medical attention promptly. Hope the information provided would be helpful. All the best.