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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Biopsy Recommended To Diagnose The Rise In PSA Level?

I was diagnosed with benign enlarged prostrate 10 years ago. Had a biospy at that time which was negative. I visit my urologist yearly. My PSA has jumped from 3.7 to 6. I take finasteride daily.My doctor wants we have another biopsy. The digital exam was normal. Is this a common approach to this spike in the PSA? Also, if my biopsy is negative what is the treatment protocol? Does my finasteride get increased? thanks
Fri, 6 May 2016
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General & Family Physician,  's  Response
Hi & Welcome.
Yes, a rise in prostate-specific antigen (PSA) is by far the most common indication for prostate biopsy to rule out cancer.
A PSA test may help detect prostate cancer at an early stage
The test doesn't always provide an accurate result. An elevated PSA level doesn't necessarily mean you have cancer. And many men diagnosed with prostate cancer have a normal PSA level. Besides cancer, other conditions that can raise PSA levels include an benign prostatic enlargement and an inflamed or infected prostate (prostatitis).
Also, PSA levels normally increase with age.
So, in addition to prostate biopsy, you may also need to undergo certain tests such as transrectal ultrasound, X-rays, or cystoscopy to rule out other causes of rising PSA level.
If the biopsy is negative the underlying cause if any as mentioned may be detected and treated along with an increase in dose of Finasteride.


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Is Biopsy Recommended To Diagnose The Rise In PSA Level?

Hi & Welcome. Yes, a rise in prostate-specific antigen (PSA) is by far the most common indication for prostate biopsy to rule out cancer. A PSA test may help detect prostate cancer at an early stage The test doesn t always provide an accurate result. An elevated PSA level doesn t necessarily mean you have cancer. And many men diagnosed with prostate cancer have a normal PSA level. Besides cancer, other conditions that can raise PSA levels include an benign prostatic enlargement and an inflamed or infected prostate (prostatitis). Also, PSA levels normally increase with age. So, in addition to prostate biopsy, you may also need to undergo certain tests such as transrectal ultrasound, X-rays, or cystoscopy to rule out other causes of rising PSA level. If the biopsy is negative the underlying cause if any as mentioned may be detected and treated along with an increase in dose of Finasteride.