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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How To Treat Pancreatitis ?

I am wondering about Gilbert's syndrome and related cancers? My older brother has pancrititis and my mother is in her final stages of pancriatic cancer. I also have a sister who has had Renal cells carsonoma. My son is currently under going test for Gilbert's syndrome and I am concerned with the family history of cancer what the results may be.
Mon, 11 Apr 2016
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General & Family Physician 's  Response
Hi thanks for asking question.
Gilbert syndrome is congenital cause of hyperbilirubinemia...In this disease there is defective conjugation of bilirubin so unconjugated hyperbilirubin...

Your family member and first degree relative suffering from various cancer.
So genetic mutation might be the cause.
Like P53 mutation...Molecular study for it carried out by using FISH or PCR......

Regular follow up and screening needed for early detection of cancerous proliferation...

Take care....

Dr.Parth
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How To Treat Pancreatitis ?

Hi thanks for asking question. Gilbert syndrome is congenital cause of hyperbilirubinemia...In this disease there is defective conjugation of bilirubin so unconjugated hyperbilirubin... Your family member and first degree relative suffering from various cancer. So genetic mutation might be the cause. Like P53 mutation...Molecular study for it carried out by using FISH or PCR...... Regular follow up and screening needed for early detection of cancerous proliferation... Take care.... Dr.Parth