Welcome to Healthcare Magic There is no cure for hypothyroidism. But effective treatment of thyroid hormone replacement by tablets you have to take usually lifetime. To lose weight you need to get your thyroid levels in normal range which is helpful to lose weight gained by hypothyroidism. But you need to make changes in diet and exercise. You need to eliminate junk food, fatty food, fried food, high carbohydrate diet like much rice,. Rather eat more fruits, green leafy vegetables which are very good for health. Drink enough water. Do brisk walking everyday for 40 minutes or join a gym and do cardio workout. Also get other hormones tested like Prolactin if you are having less periods and get scanned for ovarian cysts.