Heavyiness in center of chest and extreme pressure? I've had upper Gi series, xrays, blood tests, just about everything done on me to find whats wrong, the pressure is so bad I cry sometimes and its random and has been on going for a year, I dont smoke, I have a floppy tricusbid in my heart and take a beta blocker, sereqoeul for bipolar at night, and ativan for panic attacks. :(