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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Safe Is Taking Tamoxifen For Chest Pain And Tightness?

I have been on tamoxifen now for 3 weeks, and after 5 days of being on this drug, i have developed chest pain and tightness. It is not always there, seems to come and go. However it appears to have got progressively worse over last 12 hours. Is this likely to be a side effect of the tamoxifen, and should I contact my oncologist tomorrow about this? I am 47 years of age, was diagnosed with breast cancer Sept. 2010. Have had mascetomy,chemo, radiation. My cancer was er/pr positive 91% on pathology report. I am about 65 kgs and 1.75m in height. Are taking Genox 20mg taxoxifen. Appreciate your advice. Regards Sue-Anne
Tue, 30 Aug 2016
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Pulmonologist,  's  Response
Thanks for your question on Healthcare Magic.
I can understand your concern.
Yes, all these, chest pain and chest tightness, can be the side effects of tamoxifen.
Tamoxifen can cause drug induced gastritis and this gastritis is the likely cause for your symptoms.
I think, you will be alright with taking antacid drug prior to tamoxifen.
So take pantoprazole tablet 30 minutes before tamoxifen.
Do like this for 10 days. If your symptoms are improving then no need to worry but if chest tightness persist then consult your oncologist.
Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.
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How Safe Is Taking Tamoxifen For Chest Pain And Tightness?

Thanks for your question on Healthcare Magic. I can understand your concern. Yes, all these, chest pain and chest tightness, can be the side effects of tamoxifen. Tamoxifen can cause drug induced gastritis and this gastritis is the likely cause for your symptoms. I think, you will be alright with taking antacid drug prior to tamoxifen. So take pantoprazole tablet 30 minutes before tamoxifen. Do like this for 10 days. If your symptoms are improving then no need to worry but if chest tightness persist then consult your oncologist. Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.