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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Painful Is TACE Procedure For Liver Cancer?

My father is cirrohsis pateint from last last 5 years and Diabetic patient.. treatment was going good for cirrohsis and for diabetes using insulin from last three years..but on 17-6-2014 diagnosed with liver cancer..HCC 7.8*6.4*6.3mm..my whole family is depressed.. ..doctor advised for TACE because surgery is not possible due to cirrohsis and we can not do liver transplant ..meanwhile doctor has advised for taking soranib 200 mg..so my father is taking soranib 200 mg from last 15 days and feeling so week,loss of appetite,nausea,B.P around 150..red rashes in hand..i am totally confused with this disease dont know what is going on..please sir suggest me what should we do??as there is only 1 option TACE..should we proceed with TACE ??how painful it is??how many times we should do TACE procedure..whether TACE have any problem with cirrohsis and diabetes??what would be survival rate??sir i am attaching blood test,endoscopy and CT scan report for your investigation..please help me
Tue, 3 Mar 2015
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Radiologist,  's  Response
Hi,
Thanks for writing in.

TACE is trans arterial chemo embolization of tumor. In this technique, the artery or blood vessel supplying the tumor is approached as close to the tumor possible. This can be done by reviewing previous imaging investigations and once this is done, intra-arterial injection of chemotherapeutic drug combinations like doxorubicin, cisplatin and mitomycin into the hepatic artery, followed by lipiodol injection, Gelfoam for vessel occlusion and degradable microspheres. Once major blood supply to tumor is blocked and chemotherapy agents infused, then the tumor will not get its nutrition and will not grow or grow slowly.

The pain is controlled by giving sedatives and not more than a puncture in the groin region. The palliative effect in unresectable HCC using TACE allows local tumor control in 15 to 60% of cases and 5-year survival rates ranging from 8-43%. Please do not worry.
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How Painful Is TACE Procedure For Liver Cancer?

Hi, Thanks for writing in. TACE is trans arterial chemo embolization of tumor. In this technique, the artery or blood vessel supplying the tumor is approached as close to the tumor possible. This can be done by reviewing previous imaging investigations and once this is done, intra-arterial injection of chemotherapeutic drug combinations like doxorubicin, cisplatin and mitomycin into the hepatic artery, followed by lipiodol injection, Gelfoam for vessel occlusion and degradable microspheres. Once major blood supply to tumor is blocked and chemotherapy agents infused, then the tumor will not get its nutrition and will not grow or grow slowly. The pain is controlled by giving sedatives and not more than a puncture in the groin region. The palliative effect in unresectable HCC using TACE allows local tumor control in 15 to 60% of cases and 5-year survival rates ranging from 8-43%. Please do not worry.