has high potential for abuse and addiction by activating the psychological reward system via triggering a cascading release of dopamine
, a hormone, in the brain. As a result of methamphetamine-induced neurotoxicity
to dopaminergic neurons, chronic abuse may also lead to post acute withdrawals which persist beyond the withdrawal period for months, and even up to a year.Research has found that 20% of methamphetamine addicts experience a psychosis
which persists for longer than six months post-methamphetamine use; this amphetamine psychosis can be resistant to traditional treatment. In addition to psychological harm, physical harm, primarily consisting of cardiovascular damage, may occur with chronic use or acute overdose.Methamphetamine use has a high association with depression
and suicide as well as serious heart disease
, amphetamine psychosis, anxiety and violent behaviours. Methamphetamine also has a very high addiction risk.Methamphetamine is neurotoxic and is associated with an increased risk of Parkinson's disease.Methamphetamine abuse can cause neurotoxicity which is believed to be responsible for causing persisting cognitive deficits, such as memory, impaired attention and executive function. Over 20 percent of people addicted to methamphetamine develop a long-lasting psychosis resembling schizophrenia after stopping methamphetamine which persists for longer than 6 months and is often treatment resistant.
That means, it needs to be kicked off. Once kicked off, it will be a rebirth and new life.