hello there.Thanks for writing to HCM first of all,let me appreciate your willingness to work at an elderly age.kudos for that i have read your query and understand your concern. Yes,there are many newer drugs and newer modalities now in treating depression and related symptoms as you have enquired. I hope you are otherwise hale and healthy with no other disease as there has been no mention in the history given . from my view point,you have grown tolerant to sertraline and clonazepam over the years. Here is what i would recommend or advise if you i were your treating doctor: You can give venlafaxine a try. i would also suggest to take a psychostimulant drug like methylphenidate or modafinil which not only improves depression but also improves memory,productivity and cognition.You will get these on prescription from your doctor I think those would help you a great deal i would recommend cognitive behavioural therapy if you are willing to;in consultation with a psychiatrist Since you have said,you feel well when you golf or ski,i also would recommend distraction techniques and meditation. I would also suggest to do transcranial magnetic stimulation (TMS) ,if it is available at centres in your place.it is relatively new,but immensely effective i hope most of this works out well for for you. hope it helps. Follow up if needed further advise. good day and take care.Be happy