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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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High SGOT, SGPT, Had Donated Liver To Hep C Patient. Did Liver Operation Cause The High Levels For SGOT ?

I just did my blood test. I fasted well over 15 hours before the test was done. My only comsumption was distilled drinking water. My SGOT is 116 (0-40) and SGPT is 62 (0-53). They are both over especially my SGOT. The thing is, I was a liver doner 2 years ago to a Hep C patient. The operation was successful and my liver was all good and fully grown within 3 months (after several ultra-sound checks). I don t drink alcohol or smoke. I ate a lot at 1 point and gain some weight. 1 month ago, my BMI is 28.4. After following a fast five diet for a month, my BMI is now 25.9. I lost 8kgs in 1 month by just eating 1 meal, some fruits and snacks within a same 5 hours period each day. The rest of 19 hours just distilled water. So my blood test was done few days ago. Did my liver operation caused the high levels for SGOT or was it my recent diet plan or was it the food that I was eating the passed few months?
Wed, 12 Dec 2012
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Gastroenterologist,  's  Response
Hello, eddiench,
I want to congratulate you for donating your liver to save a
Hep-C patient. I am sure your liver has regenerated fully by
now. I am also very plesed to see that you are staying away
from anything that could cause damage to your liver.
It appears that your weight loss was fairly recent with a what
appears to be a strict diet. It is possible that you lacked good
amounts of protein in your diet. Extended periods of fasting
can cause your liver enzymes to go up. Some of the enzyme
elevation could have been present before your weight loss and
now the levels very mildly elevated , especially SGPT. Of the two,
SGPT or ALT is more important and slower to come down.
I would like you to start taking Vit-E 800 i.u. daily along with
Vit-C 1000mg. a day. Increase your proteins and limit the fat.
Moderate amount of starches are O.K.
It is possible that you were excercising as well that could add
to SGOT elevation .
I don't think that you have to worry about your liver function tests
getting worse.
I wish you well.
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General Surgeon,  Dr. Dr. Ivan Romich's  Response
Dear sir, I think that your enzymes elevation is related to your liver donating because even 2 years after liver can show signs of regeneration . I dont know the exact size of liver you ve donated ( probably 2. and 3. segment) but these finding are not unusual for liver donors. Also SGPT is only mildly elevated and if you dont have bilirubin level elevation or some particular symptoms i think there is no reason to be concerned. Of course, if you want to be sure you can do liver ultrasound with liver biopsy and viral markers to rule out some other disorder. If your weight losing was unintentional then it can be symptom of serious liver disease, but if you lost it because you wanted then you can expect that you findings will improve.

Wish you good health. Dr. Ivan Romich
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High SGOT, SGPT, Had Donated Liver To Hep C Patient. Did Liver Operation Cause The High Levels For SGOT ?

Hello, eddiench, I want to congratulate you for donating your liver to save a Hep-C patient. I am sure your liver has regenerated fully by now. I am also very plesed to see that you are staying away from anything that could cause damage to your liver. It appears that your weight loss was fairly recent with a what appears to be a strict diet. It is possible that you lacked good amounts of protein in your diet. Extended periods of fasting can cause your liver enzymes to go up. Some of the enzyme elevation could have been present before your weight loss and now the levels very mildly elevated , especially SGPT. Of the two, SGPT or ALT is more important and slower to come down. I would like you to start taking Vit-E 800 i.u. daily along with Vit-C 1000mg. a day. Increase your proteins and limit the fat. Moderate amount of starches are O.K. It is possible that you were excercising as well that could add to SGOT elevation . I don t think that you have to worry about your liver function tests getting worse. I wish you well.