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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Hepatitis B, Was Taking Lamivudine, Doctor Changed To Viread, Side Effects Of Diarrhoea, Stomach Ache. Advice?

My doctor is a specialist in tauranga NZ, I have Hep.B and he treated me with Lamivudine and he wants to change to another drug called Viread 300mg. I just started taking it 2 days ago and i don t feel very good. He said is for the protection of my liver so I don t get liver cancer . I have read in the internet you can get fatal side effects. I want to know if I will stop taking it after just two doses is there any danger to me. Please, do reply and advise me what can I do and remain safe. When I took lamivudine i didn t have any side effects, now I have diahrea and tummy aches. thanks , Mrs E.P.W Tauranga NZ . P S I do not have HIV .
Fri, 14 Sep 2012
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Internal Medicine Specialist 's  Response
Hi nelisa80,
Lamivudine is a lousy drug nowadays given the high risk of resistance of the virus to this medication (meaning that the medication stops working against the virus).
Viread is a great drug in this regards, however if you are having bad side effects and can't tolerate it you may needs to be switched to another one. There is no life threatening danger if you stop the medication, you are just at an increased risk of developing resistance to Viread as well.
You do need to be on something to prevent hepatocellular carcinoma. Another alternative is Entecavir.
Hope that helps.
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Hepatitis B, Was Taking Lamivudine, Doctor Changed To Viread, Side Effects Of Diarrhoea, Stomach Ache. Advice?

Hi nelisa80, Lamivudine is a lousy drug nowadays given the high risk of resistance of the virus to this medication (meaning that the medication stops working against the virus). Viread is a great drug in this regards, however if you are having bad side effects and can t tolerate it you may needs to be switched to another one. There is no life threatening danger if you stop the medication, you are just at an increased risk of developing resistance to Viread as well. You do need to be on something to prevent hepatocellular carcinoma. Another alternative is Entecavir. Hope that helps.