Hello and welcome to HCM.
Thank you for your query.
Let me first explain the root cause as to why your Urologist
has advised this test. A test conducted called serum PSA (prostate-specific antigen) is usually conducted in elderly males with an enlarged prostate
and is usually elevated in patients with prostate disorders or prostate cancer
. The normal range is considered to be 4.0 ng/mL and less. As your serum PSA has returned 6.0 ng/mL, we will have to suspect prostate cancer, and rule this out. For this, we will have to take a tissue sample of your prostate and test it in the laboratory for any cancer cells.
The enlarged prostate can cause stagnation of urine and thus infections, this could be the cause of the cystitis
(which is inflammation of the urinary bladder
), possibly due to an infection. The obstruction of normal flow of urine due to pressure applied on the ureter by the enlarged prostate can also lead to an infection in the kidneys and accumulation of urine, which explains the hydronephrosis
In such a scenario, where there are multiple problems being caused by one part, treating and normalizing the problematic part will treat all other problems. In your case, that is the prostate. Which is why your doctor is concentrating entirely on the prostate, and as current investigations are not giving us a healthy picture, a biopsy at this stage would be the best.
TRUS is a transrectal (through the rectum) ultrasonography
guided biopsy of the prostate. This is safe, and can easily be performed even in elderly males. Do not worry. His age should not be a concern. Please go ahead with this as it is the best option right now.
I hope I have succeeded in providing the information you were looking for. Please feel free to write back to me for any further clarifications. I would gladly help you.