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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Tiredness, Weight Gain, Knee Pain. Had Depression Earlier. All Test Done. Can It Be Hypothyroid?

Hi
Im 27 years old and suffer from tiredness and really struggling losing weight- I even gain weight on 1300 calories/day. I have had depression 2 years ago-tablets didn't do much, been referred to a physio for knee pain and had pelvic scans for lower abdomen pain all of which didn't find anything. I have really dry skin too. My TSH level is 1.45 (0.4-4.0 ref range) and Ive asked the doctor to test my T4 (at todays apt) so I should be going for that test soon but I'm just wondering could I still be hypothyroid with a normal TSH?
Fri, 26 Apr 2013
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General & Family Physician 's  Response
Hello,
Yes,it is still possible to be hypothyroid in spite of having normal TSH
There is a condition called as  HASHIMOTO'S THYROIDITIS which is auto immune in nature.The diagnosis is made on the basis of clinical picture along with finding the presence of anti bodies called as anti thyroid peroxidase and anti thyroglobulin.
 Even if one or both of these is positive, treatment will not normally be initiated for low thyroid function unless there is the presence of a raised TSH levels and possibly a low T4 level too.
However it has been seen that if you give low dose THYROXINE to such patients ( having clinical picture of hypothyroidism but with normal TSH and T4 ),there is dramatic relief in the symptoms.
Other possible causes for your symptoms could be....
Anemia
Diabetes
Low VIT D levels
You must discuss with your doctor about all these possibilities and get the required investigations done.
Thanks
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Have Tiredness, Weight Gain, Knee Pain. Had Depression Earlier. All Test Done. Can It Be Hypothyroid?

Hello, Yes,it is still possible to be hypothyroid in spite of having normal TSH There is a condition called as  HASHIMOTO S THYROIDITIS which is auto immune in nature.The diagnosis is made on the basis of clinical picture along with finding the presence of anti bodies called as anti thyroid peroxidase and anti thyroglobulin.  Even if one or both of these is positive, treatment will not normally be initiated for low thyroid function unless there is the presence of a raised TSH levels and possibly a low T4 level too. However it has been seen that if you give low dose THYROXINE to such patients ( having clinical picture of hypothyroidism but with normal TSH and T4 ),there is dramatic relief in the symptoms. Other possible causes for your symptoms could be.... Anemia Diabetes Low VIT D levels You must discuss with your doctor about all these possibilities and get the required investigations done. Thanks