Hello Thanks for posting query A large blood clot in top of right leg, in medical language it is called DVT (deep vein thrombosis) of lower limbs Tendency of blood to form clot happen when there is prolonged immobilization mostly after trauma. Spinal cord injury itself is very high risk for clot formation in deep veins. Problem of this disease is this formed clot may dislodge and travel through heart and might obstruct large artery which is known as Pulmonary artery also known as Pulmonary embolism. Pulmaonary Embolism (PE) is potential life threatening condition, people can dye immediately in main pulmonary artery is obstructed. To prevent this life threatening condition blood thinner(anticoagulant) is used (warfarin or low molecular weight heparin) and if can correct underlying risk factor then it will be required life long Management of anticoagulant is real challenging and things become more tricky if there is increased chance of blooding for example in your situation it is hemorrhoids they can bleed in the presence of anticoagulant. We usually keep balance if it actually starts to bleed then temporarily we stop blood anticoagulant and fix the bleeding problem and restart anticoagulant For any procedure or operation then again temporarily stop anticoagulant and restart initially short acting anticoagulant injections post procedure. After few days when there no increase risk of bleed then we switch on long acting oral anticoagulant You discuss with whole issue with treating doctor and request them to have good liaisoning among different specialty doctor because require of one speciality may be undesirable to other and we have to find mid way to reduce the risk of life first then reduce the morbidity Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries. Wishing you good health to your son. Dr Jeetendra Sharma Senior Consultant Critical Care