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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Positive Elisa And Western Blot. Pain In Feet, Neck And Jaws. What Does Positive IGM Mean?

I have a positive Elisa and Western blot positive IGM, negative Igg . Treated 3 weeks doxycycline back in November, Pains in feet , neck , face,jaw continuing January retested same results . 3 months doxycycline. Restested once again same results Positive igm 23, 39 bands . What does this mean? more antibiotics. ???
Thu, 25 Apr 2013
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM,

Presence of positive ELISA and Western blot test for Ig M indicates an active infection. In any infection, Ig M are the first immunoglobulins which become positive followed by Ig G. Positive Ig G indicates a past infection.
However, you have not mentioned the causative organism for which the test is done.
I can only guess that the test was performed for some bacterial infection for which doxycyclin was given.

Thanks and take care.
Dr Shailja P Wahal
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Have Positive Elisa And Western Blot. Pain In Feet, Neck And Jaws. What Does Positive IGM Mean?

Hello and welcome to HCM, Presence of positive ELISA and Western blot test for Ig M indicates an active infection. In any infection, Ig M are the first immunoglobulins which become positive followed by Ig G. Positive Ig G indicates a past infection. However, you have not mentioned the causative organism for which the test is done. I can only guess that the test was performed for some bacterial infection for which doxycyclin was given. Thanks and take care. Dr Shailja P Wahal