Hello and welcome to HCM Nephrotic syndrome does not interfere with conception. It is a kidney disorder. There are various disease processes which lead to nephrotic syndrome. Yhe most common disease process is glomerulonephritis which is caued due to damage to glomerulus of the kidney. Other diseases like diabetes mellitus , SLE, amyloidosis also lead to glomerulonephriris and thus nephrotic syndrome. Glomerulonephritis are also of various types. Some glomerulonephritis repond well to steroids and other do not. So it is important to get a kidney biopsy done and to know the exact cause of nephrotic syndrome. Relapsing and remitting is a feature of glomerulonephritis. You will heve to take the steroids whever there is relapse. Managing the dose will minimize the side effects if any. The disease process will not hinder conception. However, drugs have to be taken with caution during pregnancy. It has to be done in consultation with your treating doctor. Thank you and take care Dr Shailja P Wahal Majority of cases do not have underlyning cause. Others are secondary to infections, drugs and malignancies. There are various disease processes which lead to