Thanks for posting your query.
There is high possibility of migraine
as the symptoms suggest and migraine is the most common type of headache.
Your wife has to take anti emetics such as metoclopramide
, otherwise whatever medication will be taken for relief of headache works partially.
You should again consult with internal medicine specialist / neurologist
and should go for thorough check up.
She has to take prophylactic medication for future prevention of migrainous attacks.
As such no permanent cure is available for migraine.
Dr. Mayank Bhargava