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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Grand Mal Seizures, Absence Seizures. Taking Trileptal And Keppra. Any Suggestions?

My daughter is 31 and has Down Syndrome. At age 28 she had her first grand mal seizure. She had 2 grand mals in 2 years, but also developed complex partial seizures & absence seizures. Since January of this year, she has had 4 grand mals, one resulting in a fall. She continues to have the absence seizures. She currently takes 1500 mg trileptal each day & 1000 mg of keppra. I see a link between balance issues for her and the absence seizures. We see a neurologist but am thinking of getting a second opinion. She is having the partial & absence seizures almost daily. Am frustrated and worried that this is a way of life for her... any suggestions?
Tue, 13 Aug 2013
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Neurologist 's  Response
Hi,

Thank you for posting your query.

It is unfortunate that your daughter has epilepsy, which is uncontrolled.

For absence seizures, sodium valproate is the drug of choice. So, I think it should be included in her treatment regimen.

If she is still uncontrolled with good doses of three anti epileptic drugs, she would require evaluation for a possible epilepsy surgery.

Best wishes,
Dr Sudhir Kumar MD DM (Neurology)
Senior Consultant Neurologist
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Have Grand Mal Seizures, Absence Seizures. Taking Trileptal And Keppra. Any Suggestions?

Hi, Thank you for posting your query. It is unfortunate that your daughter has epilepsy, which is uncontrolled. For absence seizures, sodium valproate is the drug of choice. So, I think it should be included in her treatment regimen. If she is still uncontrolled with good doses of three anti epileptic drugs, she would require evaluation for a possible epilepsy surgery. Best wishes, Dr Sudhir Kumar MD DM (Neurology) Senior Consultant Neurologist