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if not adequately controlled leads to gradual decrease in kidney functioning over a period of time.
Here in father's case also same factors could be responsible for kidney injury and increase in creatinine
level.Drugs like ACE inhibitors and ARBs also decrease kidney function further,hence these should be avoided.
There is no harm in using lasix and minipress
in this case.Lasix increases urine output,avoids fluid overload and help in decreasing blood pressure.Minipress is also safe to use in this case to decrease blood pressure.
Following parameters should be monitored while being on these drugs:
3.serum uric acid.
My suggestion is have strict blood sugar control and blood pressure control to avoid further kidney damage.
Target blood pressure should be 110/70 mm of hg in this patient.
Hence for better monitoring get a nephrologist
Hope this will help you better.
Wish you good health.