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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Chronic Hepatitis C. Why Enzymes Are Tripling After Taking Tramadol?

I have chronic hep C and my enzymes have tripled in the last year. Trying to figure out why? I stopped taking oxycotin and started taking tramadol? I also started taking time released 5HTTP? My stress level is through the roof but I think I read stress does not affect hep c?
Tue, 24 Dec 2013
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Emergency Medicine Specialist 's  Response
serotonin or 5HTTP might be the cause of increase in your liver enzymes. It is metabolized in the liver and this could cause an elevation of your liver enzymes.
You need to do the following
1 Taper off your dose of 5HTTP lowering 5mg every week until you completely stop the durg.
2. Keep your weight within range.
3. Wait for 3 weeks after stopping 5HTTP and then retest your liver enzymes.
If your liver enzymes are still elevated you need to go to a gastroenterologist who will do a whole panel of tests for HepC
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Have Chronic Hepatitis C. Why Enzymes Are Tripling After Taking Tramadol?

serotonin or 5HTTP might be the cause of increase in your liver enzymes. It is metabolized in the liver and this could cause an elevation of your liver enzymes. You need to do the following 1 Taper off your dose of 5HTTP lowering 5mg every week until you completely stop the durg. 2. Keep your weight within range. 3. Wait for 3 weeks after stopping 5HTTP and then retest your liver enzymes. If your liver enzymes are still elevated you need to go to a gastroenterologist who will do a whole panel of tests for HepC