Hi and thanks for your question, the symptoms described are suggestive of a heart disorder. This is called dyspnoea on effort and deserves the expertise of a cardiologist. Hands turning blue while running is called cyanosis. Its urgent and too important to visit your cardiologist for a chest x ray, oxygen partial pressure measurements and a cardiac ultrasound. Easily getting tired and breathing difficulties are classical symptoms of heart disease, at times respiratory disease that must be investigated. usually it could a valvular heart disease a heart chamber to chamber communication. Making a definitive diagnosis becomes compelling as this helps in correcting the cause in most cases, taking specific medications, adopting particular lifestyles and certain vaccines at times that help in promoting quality of life. I suggest you visit a cardiologist for an proper physical examination and paraclinical examinations. Thanks and best regards, Luchuo, MD.