I m 47 and had a hysto 10 years ago and have 1 overy left. I did great until february 2011 after a spinal fusion. I feel I was throw into penopause, but not finding relief. Weight gain, skin feels terriable, joint pain and fatugie terriable. I m a cardio junkie and love working out, first year after fusion is when I felt the changes. weight gain is the biggest issue.