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Get blood blister on the stomach at the beginning of menstrual cycle, bleeds on popping, does not go away, oozing next to blister. Cause?

Always during the beginning of my menstrual cycle, I get a blood blister (very close to the surface of the skin) on the right side of my stomach. It is painful, rather small (the size of the end of a pencil eraser), and comes to a head. I know I should not, but sometimes to relieve the pain, I pop it. The blister itself bleeds first, very thick and dark blood until the blister is flat, but still present. Then, clear liquid comes out of a tiny hole NEXT TO the blood blister. This is odd and I do not understand why there would be two tiny holes. Is this a boil or a pimple or what is it? Why do I get these ONLY during my period and no other time?
Asked On : Thu, 11 Oct 2012
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Dermatologist 's  Response
I would be pleased to answer your question.

The fact that your blood filled lesions are raised makes the first possibility that of Leukocytoclastic Vasculitis. This is a small vessel vasculitis (inflammation of blood vessels in the skin) caused due to a variety of causes.

The second possibility would be of an autoimmune blistering condition known as Bullous Pemphigoid. In the stage before frank blistering the lesions can be flat and may appear bloody.

A third possibility would be senile purpura, but here the lesions consist of flat bruises. This would have been the first possibility for you if you didn’t have a history of the lesions being raised.

I think you most definitely require a skin biopsy from one of the representative lesions. This should be sent for regular histopathology as well as for a test known as direct immunofluorescence (DIF). Your blood clotting profile and platelet count should also be done if not done already. These tests will help narrow down the diagnosis and appropriate therapy to be started. You should see a dermatologist for the biopsy and blood work.

Hope this information is useful, please feel free to ask if you have any queries.
Answered: Thu, 11 Oct 2012
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