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Filariasis, wounds on left leg, discharge, foul smell, pain, fever, rough skin, medication for complete cure

My Mother aged 70 years and suffering with Filariasis since 1 year effected with left leg since last fifteen days due to this she is continuously getting wounds on her leg with foulish smell discharge and getting pain and fever also. Skin is became very ruff. kindly suggest the best medication,is it completely curable ,how much time does it take to heal her wounds.I will be highly thankful to you for guidance.
Asked On : Sun, 15 Apr 2012
Answers:  1 Views:  194
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Diseases and Conditions
General & Family Physician 's  Response
Hello and welcome to

The following is information from WHO (World Health Organization) regarding this disease process.

Lymphatic filariasis is infection with the filarial worms, Wuchereria bancrofti, Brugia malayi or B. timori. These parasites are transmitted to humans through the bite of an infected mosquito and develop into adult worms in the lymphatic vessels, causing severe damage and swelling (lymphoedema). Elephantiasis – painful, disfiguring swelling of the legs and genital organs – is a classic sign of late-stage disease.

The infection can be treated with drugs. However, chronic conditions may not be curable by anti-filarial drugs and require other measures, eg. surgery for hydrocele, care of the skin and exercise to increase lymphatic drainage in lymphoedema.

The recommended regimen for treatment through mass drug administration (MDA) is a single dose of two medicines given together - albendazole (400 mg) plus either ivermectin (150-200 mcg/kg) in areas where onchocerciasis (river blindness) is also endemic or diethylcarbamazine citrate (DEC) (6 mg/kg) in areas where onchocerciasis is not endemic. These medicines clear microfilariae from the bloodstream and kill most of the adult worms.

Annual treatment of all individuals at risk (individuals living in endemic areas) with recommended anti-filarial drugs combination of either diethyl-carbamazine citrate (DEC) and albendazole, or ivermectin and albendazole; or the regular use of DEC fortified salt can prevent occurrence of new infection and disease.

As to the healing of your mother's wounds, that will depend on her immune status and if the filiariasis has been successfully treated. Contact your local health care provider for the medications mentioned above.

Be well,
Dr. Kimberly
Answered: Sun, 15 Apr 2012
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