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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Feels Tired, Mono Disease, Elevated CPK, Low Testosterone

My 30 year old son had been feeling tired and achy over several weeks...thought he might have mono. His doctor did blood tests which showed slightly elevated CPK (around 350-375) and also low testosterone . They are treating the low T with meds but I am concerned there may be an underlying cause which has not been diagnosed. For reference, I am familiar with CPK enzyme levels because my other son, age 26, has LGMD2A (calpainopathy) and his levels are several thousand.
Mon, 28 Oct 2013
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Cardiologist 's  Response
Dear patient,

Thanks for your concerns. Indeed, it is quite rare for infectious mononucleosis, caused by the virus Epstein-Barr, to cause rhabdomyolysis (elevation from CK derived from skeletal muscle); I agree that other differential diagnoses, including one of the many inflammatory myopathies, should be entertained. A rheumatologist may be better versed to triage such encounter.

Yours truly,

Dr Brenes Salazar MD
Mayo Clinic MN

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Feels Tired, Mono Disease, Elevated CPK, Low Testosterone

Dear patient, Thanks for your concerns. Indeed, it is quite rare for infectious mononucleosis, caused by the virus Epstein-Barr, to cause rhabdomyolysis (elevation from CK derived from skeletal muscle); I agree that other differential diagnoses, including one of the many inflammatory myopathies, should be entertained. A rheumatologist may be better versed to triage such encounter. Yours truly, Dr Brenes Salazar MD Mayo Clinic MN