Welcoem to HCM! I have gone carefully through your question and it reflects that you have elevated liver enzymes and sore ness all over body, lethargy and you are on Paxil. what is not there is the duration from which you are taking Paxil and If you have any report of liver enzymes prior to taking Paxil. from my clinical experince I can say that Paxil would normally not lead to such high enzyme level and you do need a through medical examination. I doubt that you started Paxil for treating lethargy, though you never mentioned it clearly. What I feel that you are lethargic because you appear to have some kind of liver problem and not depressed ( for which Paxil might have been started). Had I been at your place I would go and see a physician, or some gastroenterologist and get complete check up. He would go for an ultra sound abdomen, complete blood counts, kidney function, lipid profile, thyroid function and sugar levels. These all may look a lot to you but I can tell that you really need to get them done and see what is going on inside you. you have not mentioned if you take any kind of alcohol/ substance of abuse, which needs to be stopped altogether. As your liver enzymes are increased, it is good if you stop oily and icy food altogether. please take adequate water, and ask someone to take you to a good doctor. at least get the investigations and you may then decide if you want to continue Paxil or not. Hope you get well soon feel free to ask more queries. Dr. Manisha Gopal.