Hello, taffis, Elevated liver enzymes could be caused by a number of factors. Hepatitis viruses and other viral diseses such as mononucleosis can cause this. Certain genetic enzyme deficiency can do this. In western culture, alcohol is number one cause. Next is gallbladder and bile duct issues, pancreas problems can cause liver test abnormalities. Most importantly, drugs both over the counter and prescription drugs can elevate liver enzymes. Auto-immune diseases such as lupus, rheumatoid arthritis can affect liver and kidneys. I am glad that your MRI tests, endoscopy and other blood work were all normal. As for Flu shot causing elevated liver enzymes , clinically we don t see it unless as part of severe allergic reaction to the shot. Influenza virus itself can cause elevated liver enzymes during active infection. Hope this gives you some idea of where to look. I wish you well.