Hello, thanks for using health care magic. All the above drugs are safe in pregnancy. But the real question to address is why the threatened abortion. Threatened abortion could be caused by infections, chromosomal abnormalities in the foetus, as well as insufficient progesterone. It is for that reason that the doctor has given you progesterone so that in case of an insufficiency, it should help. However, the use of trenaxa is not well understood in preventing threatened abortion rather it will reduce bleeding. You should get urine analysis done and continue the duphaston which is a progesterone until 13 weeks and have a lot of bed rest and most importantly no sexual intercourse for now until all becomes normal. Hope this helps. Dr Achuo