The etiology of autoimmune hepatitis
is unknown. Several factors (eg, viral infection, drugs, environmental agents) may trigger an autoimmune response and autoimmune disease
For more than 3 decades, corticosteroids
, either alone or in combination with azathioprine
, have been the mainstays of drug therapy for patients with autoimmune hepatitis.
The prognosis of autoimmune hepatitis depends primarily on the severity of liver inflammation. Patients with a severe initial presentation tend to have a worse long-term outlook than patients whose initial disease is mild.
In children with autoimmune hepatitis, 70% require treatment until adulthood. Many patients already have cirrhosis at the time of diagnosis. Almost 20-25% of children with autoimmune hepatitis die or require liver transplantation
as a result of the disease.
You have to continue giving this drug to her and the only definitive treatment at the moment is liver transplant.