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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Done Endoscopy For Barretts. Histroy Of Barretts Test From Two Endoscopies Negative. Positive Result Possible?

Hello

I had two endoscopies last year and biopsies on both occasions came back negative for Barretts. I had my third endoscopy yesterday and I have to wait 2 to 3 weeks for results. I suppose what I would really like to get your view on is the following: from your experience and knowledge can you tell me if this is a usual situation? Would you be surprised if the results are positive after two negative results?

Many Thanks

Brendan
Mon, 24 Jun 2013
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Critical Care Specialist 's  Response
Hi thanks for your question.
Barretts esophagus is diagnosed during EGD that is esphago gastro duodenoscopy and it is confirmed by biopsy. Yes this very common situation in which squamoous mucosa of esophagus is replaced by gastric mucosa, commonly occur due GERD that is gastro intestinal disorder. Yes this is possible that after two negative biopsies the third biopsy turns out to be positive. This purely depends upon the site, from where biopsy is taken and it is possible that during previous 2 procedures biopsy might have not been taken from correct site.
Hope this answers your question
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Done Endoscopy For Barretts. Histroy Of Barretts Test From Two Endoscopies Negative. Positive Result Possible?

Hi thanks for your question. Barretts esophagus is diagnosed during EGD that is esphago gastro duodenoscopy and it is confirmed by biopsy. Yes this very common situation in which squamoous mucosa of esophagus is replaced by gastric mucosa, commonly occur due GERD that is gastro intestinal disorder. Yes this is possible that after two negative biopsies the third biopsy turns out to be positive. This purely depends upon the site, from where biopsy is taken and it is possible that during previous 2 procedures biopsy might have not been taken from correct site. Hope this answers your question