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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Tysabri Infusions Cause Elevated Bilirubin Levels In Blood?

Does tysabari infusions cause elevated bilirubin levels? I have been on infusions for 1 and a half years. What is a normal level and at what point should I become concerned. Ny m.d. Says no big deal some people have height bilirubin counts normally.
Thu, 4 Sep 2014
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Geriatrics Specialist,  's  Response
Hi,
Thanks for asking.
Based on your clinical history and query, my opinion is as follows:
1. Tysabri infusions is known to caused elevated bilirubin levels and hence jaundice secondary to liver damage.
2. You need not worry about bilirubin levels. Check for levels of ALT and AST. They are more specific indicators.
3. High bilirubin levels is an indicator of liver damage. However, some people with inherited syndromes like Gilberts syndrome can have high bilirubin levels normally also.
Hope it helps.
Any further queries, happy to help again.
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Does Tysabri Infusions Cause Elevated Bilirubin Levels In Blood?

Hi, Thanks for asking. Based on your clinical history and query, my opinion is as follows: 1. Tysabri infusions is known to caused elevated bilirubin levels and hence jaundice secondary to liver damage. 2. You need not worry about bilirubin levels. Check for levels of ALT and AST. They are more specific indicators. 3. High bilirubin levels is an indicator of liver damage. However, some people with inherited syndromes like Gilberts syndrome can have high bilirubin levels normally also. Hope it helps. Any further queries, happy to help again.