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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Low Progesterone Level Affect Pregnancy Test Results?

I am 20 days late for my period and have a possible progesterone defieciency?? , i have done 2 pregnancy tests but both are negative. could i be pregnant? having lots of signs and symptoms pf pregnancy. Does low progesterone affect pregnancy testing? thanks
Fri, 14 Nov 2014
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OB and GYN Specialist,  's  Response
Hello,
If you are already 20 days over due and your pregnancy test is negative then for sure you are not pregnant.
Progesterone deficiency or luteal phase defect can cause intermenstrual spotting or breakthrough bleeding but not amenorrhoea.

If you are having signs and symptoms of pregnancy which mimic the same as that of premenstrual syndrome then you may opt to wait for 3 days nad then can opt for withdrawal bleed with progesterones like MPA ( medroxy progesterone acetate) 10mg twice a day for 5 days. you may then wait for another 7 days and your periods would resume within 7 days.

Also to confirm progesterone deficiency get a midcycle serum progestrone test done to confirm the diagnosis.
regards.
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Does Low Progesterone Level Affect Pregnancy Test Results?

Hello, If you are already 20 days over due and your pregnancy test is negative then for sure you are not pregnant. Progesterone deficiency or luteal phase defect can cause intermenstrual spotting or breakthrough bleeding but not amenorrhoea. If you are having signs and symptoms of pregnancy which mimic the same as that of premenstrual syndrome then you may opt to wait for 3 days nad then can opt for withdrawal bleed with progesterones like MPA ( medroxy progesterone acetate) 10mg twice a day for 5 days. you may then wait for another 7 days and your periods would resume within 7 days. Also to confirm progesterone deficiency get a midcycle serum progestrone test done to confirm the diagnosis. regards.