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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Mirtazapine Causes Irregular Periods?

Hello, I started taking mirtazapine in late December. I was on a steady 30 mg dose. I have missed my period the last two months, and have taken three pregnancy tests to rule that out. My psychiatrist doesn t think that it is a side effect of the medicine, but I ve read in multiple places that it is. My periods have never been very regular but this is out there even for me. Thanks!
Mon, 16 Jan 2017
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General & Family Physician 's  Response
Hi,

Mirtazapine is unlikely to cause irregular periods. Mirtazapine is an antidepressant which is used to treat major depression. Its common side effects include severe sedation, constipation, drowsiness, increased serum cholesterol, increase appetite and weight gain. It is not known to cause irregular periods. Irregular periods could be due to stress, anxiety, emotional disturbance, erratic eating habits, smoking, alcohol, ingestion of certain medications that affect the hormonal balance.

Other than that, conditions like hypothyroidism, diabetes, polycystic ovarian disease, must also be ruled out. For this, I advise you to have a thorough gynecological check up including certain tests such as pelvic ultrasound scan, hormonal tests including FSH, LH, TSH, Prolactin, OGTT, DHEAS, Free testosterone, and Lipid profile. Based on the findings, the need for the treatment can be considered.

Hope the advice given above would be useful. Let me know if I can assist you further. A feedback is appreciated.

Regards,
Dr. Mohammed Taher Ali
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Does Mirtazapine Causes Irregular Periods?

Hi, Mirtazapine is unlikely to cause irregular periods. Mirtazapine is an antidepressant which is used to treat major depression. Its common side effects include severe sedation, constipation, drowsiness, increased serum cholesterol, increase appetite and weight gain. It is not known to cause irregular periods. Irregular periods could be due to stress, anxiety, emotional disturbance, erratic eating habits, smoking, alcohol, ingestion of certain medications that affect the hormonal balance. Other than that, conditions like hypothyroidism, diabetes, polycystic ovarian disease, must also be ruled out. For this, I advise you to have a thorough gynecological check up including certain tests such as pelvic ultrasound scan, hormonal tests including FSH, LH, TSH, Prolactin, OGTT, DHEAS, Free testosterone, and Lipid profile. Based on the findings, the need for the treatment can be considered. Hope the advice given above would be useful. Let me know if I can assist you further. A feedback is appreciated. Regards, Dr. Mohammed Taher Ali