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Does CCP Positive And Ocular Manifestations Predict Early JIA Diagnosis For Child?
I am seeking expert opinions on underlying etiology for bilateral uveitis.
A five-year old boy was diagnosed as bilateral uveitis with posterior synechia.
Before oral administration of Medrol and cyclosporine (CsA), ANA was positive, RF was negative, CSR was negative, and no swollen joint has been found by a pediatric rheumatologist.
After three months of Medrol and CsA, further lab tests including anti-ccp antibody were conducted, the anit-ccp antibody test is slightly higher than the reference value, i.e., slightly positive (however, I have no idea how the Medrol and CsA have changed the anti-ccp antibody titre).
Here is my question: does the above information including ccp positive and ocular manifestations predict early JIA (JRA) diagnosis?
A five-year old boy was diagnosed as bilateral uveitis with posterior synechia.
Before oral administration of Medrol and cyclosporine (CsA), ANA was positive, RF was negative, CSR was negative, and no swollen joint has been found by a pediatric rheumatologist.
After three months of Medrol and CsA, further lab tests including anti-ccp antibody were conducted, the anit-ccp antibody test is slightly higher than the reference value, i.e., slightly positive (however, I have no idea how the Medrol and CsA have changed the anti-ccp antibody titre).
Here is my question: does the above information including ccp positive and ocular manifestations predict early JIA (JRA) diagnosis?
Thu, 26 Dec 2013
Hello,
I have studied your case with diligence.
Accp is 98 percent specific for RA so it is more reliable for diagnosis of RA then RA factor.
Juvenile Rheumatoid arthritis may involve small joints and early morning stiffness in joints, If clinical and pathological reports match then early JRA diagnosis can be predicted.
Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries.
Wishing you good health.
I have studied your case with diligence.
Accp is 98 percent specific for RA so it is more reliable for diagnosis of RA then RA factor.
Juvenile Rheumatoid arthritis may involve small joints and early morning stiffness in joints, If clinical and pathological reports match then early JRA diagnosis can be predicted.
Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries.
Wishing you good health.
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