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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Benlysta Cause Problems In Pancreas?

I m trying to find out if Benlysta can cause Pancreas. If it does, do I need to contact the company to report my issues? I was on Benlysta from July 2011 until January 2014. I had to stop treatment because I had a mass in the pancreas. In March 2014, I had a distal pancreatectomy with spleenectomy. I have a new spot on the pancreas that the doctors are keeping an eye on. I also had interstitial fibrosis in the pancreas. I was hypoglycemic before surgery and I m currently taking Invokana twice a day, Metformin 1-2 twice a day and sliding scale Novalog. The doctors haven t let me resume the Benlysta infusions and I saw on Medsfact.com that there could be possibly related to Benlysta. Any additional information would be helpful.
Fri, 18 Dec 2015
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General & Family Physician,  's  Response
dear friend

benlysta or Belimumab is a monoclonal antibody that affects the actions of the body's immune system. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage. it acts on an immune cell component called the B cell.

it has side effects but most of them relate to reduced immunity.

to my knowledge there is no such observation yet reported which pertains to the observation you have made.
since you have now a co morbidity and more chances of more severe side effects of the drug its possible it is now not recommended for use by you.

can you please let know what was the histopath finding of the pancreas lump may be it can shed some light on the issue
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Does Benlysta Cause Problems In Pancreas?

dear friend benlysta or Belimumab is a monoclonal antibody that affects the actions of the body s immune system. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage. it acts on an immune cell component called the B cell. it has side effects but most of them relate to reduced immunity. to my knowledge there is no such observation yet reported which pertains to the observation you have made. since you have now a co morbidity and more chances of more severe side effects of the drug its possible it is now not recommended for use by you. can you please let know what was the histopath finding of the pancreas lump may be it can shed some light on the issue