is TCA [tricyclic antidepressant] and tramadol is [opioid analgesic], and going through their therapeutic profile:
. Increased risk of seizures are there if both are used simultaneously.
. Increased risk of Serotonin syndrome
is more with SSRI (selective serotonin reuptake inhibitors) or MAOIs (mono amine oxidase inhibitors)
2. ADR [adverse drug reaction] of both drugs when taken together or as single are: postural hypotension
, dizziness, tachycardia
,palpitations, [symptoms in your history]
3. There is no laboratory test for serotonin syndrome. Therefore diagnosis is by symptom observation and investigation of the patient's history, check with your Attending doctor, seek immediate medical attention.