hi i had gone through your query and understand your concerns.
initial aggravation is transient and little noticed in acute diseases of the homeopathic
but it is very often in chronic diseases.usually occur during first 8 to 10 days of treatment.
the given treatment is wright or wrong tell by some symptoms.
initial aggravation is succeeded by a period of amelioration is called as a POSITIVE PHASE; it indicates the treatment progressive and in way of curing your sufferings,and it is is due to reaction of the deranged vital force.
initial aggravation is succeeded by a period of aggravation which means no amelioration at all, indicates NEGATIVE PHASE OF TREATMENT;in such cases the prognosis is very bad.
I hope this is helpful for you, thank you