Well when one is allergic to some drug like you had with plaqenil ( hydroxychloroquine
). , one may suffer from severe allergic reactions even anaphylactic shock
also on consuming the drug . But these reactions recur only when you take the same drug again . so, since you know that you are allergic you should tell your doctor that he should not prescribe this medicine . Regarding lupus
, there are many other dugs namely steroids
and immunosupressive medications on which you could be started . You should get in touch with a rheumatologist
to assess you disease activity , organ involvement and then accordingly treat you .
Get well soon .