Hello and welcome to HCM,Hereditary spherocytosis
is a hereditary disorder which is transmitted as autosomal dominant trait or autosomal recessive trait.
It will not manifest in children when transmitted as autosomal recessive trait.
A peripheral blood smear examination shows more than 50% spherocytes.
Hereditary spherocytosis is confirmed by osmotic fragility test.
Anemia with low MCV could be due to iron deficiency anemia
What is the status of MCH, MCHC, RDW
The result of all these parameters will determine whether there is any evidence of spherocytes in your children since MCV is low in spherocytosis also.
Osmotic fragility test should also be done to confirm or rule out spherocytes.
Thanks and take care
Dr Shailja P Wahal