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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Diabetic, Renal Failure, On Seizure Med. Long Term Effects Of This Condition? Paralysis?

My brother has been a diabetic for at least 30 years, to combat that situation a recovering alcoholic. He has had 2 strokes, is considered legally blind but still able to work, and is in 4th stage renal failure . Recently he has been experiening severe neuropathy thru out his body( face , chest hands feet , legs and arms) explains it as numbness which goes into needle like bee sting . The doctor has him on a seizure med to control but doesn t seem to help. Just like to know beside the complex b12 he is now taking to ease up the pain- what is the is the long term effects of this type of condition and can it be paralyzing and is there anything else that should be addressed to help (ex. special diet) Thanks Maureen
Mon, 7 Oct 2013
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General & Family Physician 's  Response
Hello,
The longterm complications of diabetic peripheral neuropathy ( DPN ) are foot ulceration and possible amputation of limbs in cases where gangrene develops.
The foremost treatment of DPN is tight control of blood sugar levels.
The three most important drugs approved by US FDA for treatment of DPN are
Anti convulsants GABAPANTINE and PREGABLIN
Antidepressant DULOXETINE
And
Long acting opioid TAPENTADOL ER.
These drugs have been tried in different combinations but with limited success only.However still lot of studies are being done for better treatment plans.
The fact is that inspite of best available treatments,DPN is a slowly progressive disease,at the moment.
Thanks
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Diabetic, Renal Failure, On Seizure Med. Long Term Effects Of This Condition? Paralysis?

Hello, The longterm complications of diabetic peripheral neuropathy ( DPN ) are foot ulceration and possible amputation of limbs in cases where gangrene develops. The foremost treatment of DPN is tight control of blood sugar levels. The three most important drugs approved by US FDA for treatment of DPN are Anti convulsants GABAPANTINE and PREGABLIN Antidepressant DULOXETINE And Long acting opioid TAPENTADOL ER. These drugs have been tried in different combinations but with limited success only.However still lot of studies are being done for better treatment plans. The fact is that inspite of best available treatments,DPN is a slowly progressive disease,at the moment. Thanks