Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
123 Doctors are Online

Diabetic, on repaglinide, sugar levels are still the same. What can be done?

my mother around 60 years is diabetic & was on with 4mg of glimipride & 1000mg of metformin daily. Her FBS was 210, PPBS 450. Now she was changed to repaglinide 2mg before every meals and with 1000mg of metformin daily. she does not take glimipride now. But her sugar levels are still the same. is their a requirement of increasing the dose of repaglinide. Kindly suggest
Asked On : Thu, 28 Mar 2013
Answers:  3 Views:  38
Report Abuse
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions
Internal Medicine Specialist 's  Response
Welcome to HCM,
Your mother is diabetic and on oral hypoglycaemic drugs, I presume she must be having diabetes for few years now,her blood sugar is not controlled at all.
Please visit a good Physician or Endocrinologist and if there is need please hospitalize her for control of diabetes as there is secondary failure of oral drugs she will need to control blood sugar with Insulin injection therapy.Just increasing the dose or changing oral drug will not help in such case.Yes it is possible to use insulin and oral drug simultaneously to have good result.
If she is not taking care of diet she should take diet as advised and investigate for presence of any infection.
Once her sugar is controlled then she must walk daily to increase physical activity.
There are very good Basal insulin and pre mixed insulin which can be prescribed to her, she can also do a carbohydrate count in diet and adjust dose of insulin accordingly.
Take care
Good Luck
Answered: Fri, 29 Mar 2013
I find this answer helpful

 1 user finds this helpful

Internal Medicine Specialist Dr. Maruti Karale's  Response

Thanks for writing to HCM.

Yes,she needs dose adjustment and even may require third anti-diabetic drug if not controlled with 2 drugs.

The recommended dose range for repaglinide is 0.5 mg to 4 mg preprandially up to four times daily. Dosage adjustments should be determined by blood glucose response. The dose can be adjusted up to 4 mg until a satisfactory blood glucose response is achieved. At least one week should elapse after each dose adjustment to assess the patient's response. The maximum recommended daily dose of repaglinide is 16 mg.

Even metformin dose can also be increased up to 2 gm per day.

Get other investigations done for prevention and treatment of complications of diabetes.

Hope this could help you.

Wish your mom good health.

Answered: Fri, 29 Mar 2013
I find this answer helpful

 1 user finds this helpful

General & Family Physician Dr. Gopal Krishnam Raju's  Response
better to shift to insulin otherwise her systems might be get destroyed :)
Answered: Fri, 29 Mar 2013
I find this answer helpful
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]


Loading Online Doctors....
© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor