Thank you for your question.
If you do not have any symptoms like vomiting
with these raised enzyme levels and if your bilirubin
is normal I would suggest that you should carry on using these medications.
It is recommended that if the SGPT is more than five times the upper limit or normal in an asymptomatic patient (meaning you are not having any symptoms) and more than 3 times the upper limit of normal in a symptomatic patient (meaning that you are having symptoms such as vomiting) only then should alternate drugs be considered.
Therefore at the present moment I would monitor your counts on a weekly basis.
medications will be changed at the end of two months of you taking them to a regimen that will not contain PZA which is considered one of the most hepatotoxic medications (medications that can affect the liver
enzymes the most).
Another very important thing is that you must keep your diabetes
well under control because if that is not the case then the antituberculous medications may not be as effective and your tuberculosis
may not be cured.
You should remain in close follow up with your doctor and I would suggest repeating these enzymes on a weekly basis.