Mr Pandey , Amaryl MP- 2 contains glimepiride
1 mg, metformin
500 mg, pioglitazone
15 mg and ObiMet Gx2 contains (glimepiride 2 mg, metformin 500 mg) , as per your questions you are taking each tablet two times daily meas , the total dose of glimeperide will be 6 mg per day (Maximum daily dose). The best way to reduce weakness and other problems related to diabetes is shift to Insulin therapy
, for that you talk to your medical practitioner.
Hope everything will be smooth
all the best.